default or selected kernelversion does not have config value CONFIG_I2C_ISA.
Result is shown for kernelversion 5.15.113

CONFIG_I2C_ISA (not configurable)

modulename: i2c-isa.ko

configname: CONFIG_I2C_ISA

Linux Kernel Configuration
└─>Device Drivers
└─>I2C support
└─>I2C Hardware Bus support
└─>I2C_ISA
In linux kernel since version 2.6.20 (release Date: 2007-02-04)  
source code: